The expert explains why the drug is considered the greatest innovation on the market
Recently, a study released by the Congress of the American Diabetes Association (ADA, its acronym in English), in San Diego (USA), has put the spotlight on a new drug for obesity. This is because, according to research, the substance has the ability to promote a 24.2% weight loss in less than a year. That is, a person weighing 100 kg could reach up to 75.8 kg in less than 12 months using the drug.
The novelty has also thrilled the medical society, as its findings have shown that the drug can also negatively affect type 2 diabetes and, in the future, replace the need for bariatric surgery. Therefore, Dr. Isis Toledo, endocrinologist and metabolologist of SBEM (Brazilian Society of Endocrinology and Metabology), lists 5 relevant points that must be monitored after the arrival of retatrutides on the market. I wait!
1. Continuous use of drugs
One factor that people have a hard time understanding, according to Dr. Isis Toledo, is which treatment against obesity occasionally it must be continuous. “When the patient loses weight, for example 20 kg, he comes out of this treatment period with 2,000 calories more from hunger, which is something physiological, and this is the main reason why people regain weight when they stop treatment or even when they continue, ”explains the professional.
In his view, drugs like this, which act on different hormones, become useful tools in prolonged treatments. “When we have the therapeutic options that will come in the future, with these discoveries, they become important, especially when the patient is hungrier and needs to maintain the weight achieved,” she says.
2. Delusion with the results of medicine
Dr. Isis Toledo explains an important part of the revelations about retatrutida, which concerns its effect linked to the BMI (Body Mass Index). This is measured by dividing a person’s weight by their height squared.
“This study with the molecule showed that the people who lost the most weight were the ones who had the highest BMI. This is interesting, because when we see the trivialized use of Ozempico, needs to be explained so people are not deluded that thinner patients will achieve these weight loss rates. The study showed that those who lost the most were those with the highest BMI,” she adds.
3. Effects of the substance on women
According to the specialist, another point that has attracted a lot of attention is that the percentage of weight loss of women was greater than that of men. “This is very interesting, because women have more difficulty losing weight. This is because this molecule is a triagonist, which integrates the action on GLP-1 (hormone created by the small intestine), GIP (also released in a more upper of the delgado intestine) and glucagon, which is different from reatatrutida, i.e. it is a medicine that contains 3 hormones”, defines the endocrinologist.
4. Positive results in blood pressure and visceral fat
Emphasizing that the molecule is still going into phase 3 studies, Dr. Isis Toledo highlights the effect of the retatrutida blood pressure. “It improved the systolic (highest on the meter) and diastolic (lowest on the meter) blood pressure parameters,” says the doctor, adding another unprecedented effect, which concerns fat in the organs.
“This point has caused a stir and will deserve attention in our clinical practice: retatrutida reduced, normalized 80% to 90% fat in the liver, which is super important,” underlines the specialist, informing that it is the visceral fat that increases inflammatory markers and the risk of cardiovascular disease.
5. Lack of data on side effects
Finally the dr. Isis Toledo highlights the lack of data on the adverse effects of retatrutida and takes the opportunity to explain an important point about the side effects of diet drugs.
“Many people still think that the side effects of Ozempic, for example, are nausea, nausea, are responsible for weight loss. The person thinks like this: “I used Ozempic, I got nauseous, so I didn’t eat.” Associate nausea with weight loss. But it’s not true. Patients with and without side effects induced the same weight loss, overall, in research,” concludes the endocrinologist.
By Michelly Souza
Source: Terra
Ben Stock is a lifestyle journalist and author at Gossipify. He writes about topics such as health, wellness, travel, food and home decor. He provides practical advice and inspiration to improve well-being, keeps readers up to date with latest lifestyle news and trends, known for his engaging writing style, in-depth analysis and unique perspectives.
