What’s new for the treatment of melasms

What’s new for the treatment of melasms


Melasms are stains on the skin, especially on the face, with difficult treatment

Oral and combined therapies, new cosmeceutic and even artificial intelligence are new promises to reduce points




Taking care of melasma has always been a challenge for dermatology. Therefore, scientists focus more and more on research to reach treatments that improve the appearance of dark spots on the skin, especially in the areas exposed to the sun like the face.

The proof of this is that during the international course of aging sciences), the main congress of dermatology and science of aging, which was conducted in February in Paris, some studies showed important steps in the treatment of melasma.

Progress in the treatment of melasma

One of the salient moments was a master class conducted by Brazilian dermatologists Valéria Campos, Celia Kalil and Patricia Felipe França, which showed the effectiveness of oral supplementation with DecarboxyCarnosinehcl (Glycoxy®) in the melasma treatment. According to doctors, the ingestion of 200 mg per day of this substance for 60 days led to a significant improvement of 60% of the patients evaluated in the studies.

The Decarboxycarnosin HCL (Glycoxyl®) is a compound derivative of Carnosin known for its antioxidant and anti -jetty properties. Glying is a process in which the sugars are linked to proteins, forming advanced glying final products (age), which contribute to the skin aging and to the emergence of imperfections.

“This compound helps to treat melasma because it inhibits age formation, which worsens hyperpigmentation,” says dermatologist Otávio Macedo. “In addition, it is a powerful antioxidant: it neutralizes the free radicals that stimulate the production of melanin. Therefore, it helps to control the inflammatory processes that aggravate the melasma”, complete

Combined therapies

Another point of view was the use of combined therapies that mix skin care with injection procedures and advanced technologies. They are non -ablative fractional laser and monopular radiofrequency, as coolfase. These are therapies that help to treat vascularization problems associated with melasma. The goal is to improve results and minimize recurrence.

The technologies combined with other forms of regenerative therapy, such as PDRN (composed of fragments of salmon DNA) and exosomes (nanoparticles derived from stem cells, such as Exiocobio), allow these products to penetrate better in the skin. “With laser and radiofrequency” we open the road “to absorb these substances on the skin, which we call” release of drugs “. And they accelerate recovery, minimize post-proceduic inflammation and help modulate skin pigmentation,” says Otávio Macedo.

Artificial intelligence in favor of diagnosis

The technology was also described in the symposium. Tools based on artificial intelligence, such as the skin analyzer and the square mind, are innovating the diagnosis of melasma. Therefore, a more accurate evaluation of the type and depth of pigmentation is possible. Therefore, the doctor may indicate the most assertive treatment.

New cosmeceutics for the treatment of melasms

Cosmocêutics are products that combine cosmetics and pharmaceutical items for better treatment. The procedures performed in the office and studies for the treatment of Melamsa are in full evolution. An example is the Cible Skin, a line of French skin care products that should arrive in Brazil by the end of the year. This line contains a resource that promises to cause cellular reprogramming and therefore intense rejuvenation and bleaching of the skin.

Source: Terra

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