The new substance carries a durability differential and is expected to be commercialized in 2023
Botulinum toxin is well known and used to correct fine lines and fine lines. Now something new has just arrived: DAXI, a shortened term from English whose scientific term is daxibotulinumtoxinA-lanm.
Like the botulinum toxin we already know, DAXI is also an injectable type A toxin that causes muscle paralysis in the region where it is applied to reduce expression lines.
The novelty, however, brings a differential relative to the type of protein injected, which guarantees to have a durability up to three times greater than the traditional botulinum toxin.
The findings regarding the use of DAXI were published in a study published this week by Revance Therapeutics, in the Journal of American Dermatology. It is worth mentioning that the new substance has been approved by the FDA, an American regulatory agency.
“This new treatment can be used in several areas to improve and invigorate the skin, strengthen tissues and give the tone that the patient is looking for, smoothing the signs of expression associated with aging,” explains dermatologist Valéria Campos, a specialist at Harvard. Medical School, member of the Brazilian Society of Dermatology.
“According to the study, another big difference is the method of application, which is done in a single injection, and not by areas, which makes the method more painless,” says the dermatologist.
According to the results obtained from the study with DAXI, the new substance has an efficacy of 6 months or more. This means that the muscles in the area where it is applied only begin to sag after 28 weeks of the procedure.
It is important to say that other similar toxins tend to last three to four months at most. “It seems that DAXI can also be used like all type A toxins, already used in Brazil, both from an aesthetic and therapeutic point of view, so validation by Anvisa is still necessary for this novelty to arrive here”, Valeria emphasizes.
Another benefit of DAXI is its durability, as pandemic, stress, constant, high-impact physical activity can shorten the length of the procedure.
“My experience in the studio demonstrates a significant decrease in the duration of the toxin. Another important point is the interval between applications, which must be at least four months, because the touch-ups can trigger a vaccine effect that makes the effect lose the effect. treatment, “says the doctor.
In the United States, the new substance was approved for marketing on Thursday, September 8. Approval has been given by the Food and Drug Administration (FDA), which regulates the use of these injectable neuromodulators.
“It is now a matter of time before DAXI can be used here, but the expectations are very promising,” emphasizes the dermatologist.
In addition to helping correct expression lines, according to the doctor, DAXI may also prove effective for treating other conditions, including rosacea, migraines, scars, hyperhidrosis, and even depression, in addition to the already known botulinum toxin.
American doctor Michelle Green conducted a study which points out that patient tests have shown the maximum efficacy of DAXI during clinical trials. The new substance was about 97% effective, a percentage higher than the average of all products in the same category.
Another relevant finding is that, according to the manufacturer, 6% of users tested with DAXI experienced headaches after application. Furthermore, only 2% had problems with eyelid dropping. “Like any other toxin, some patients may experience negative side effects, which can be resolved in the office by a dermatologist,” explains Dr. Valeria.
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Source: Terra
Benjamin Smith is a fashion journalist and author at Gossipify, known for his coverage of the latest fashion trends and industry insights. He writes about clothing, shoes, accessories, and runway shows, providing in-depth analysis and unique perspectives. He’s respected for his ability to spot emerging designers and trends, and for providing practical fashion advice to readers.
