The launch promises to reduce excess body weight without the need for bariatric surgery
Known as Mounjaro, tizerpatide promises to be a major new evolution in the treatment of obesity. This is because this drug has achieved greater efficiency in weight loss than any other drug available for this purpose. It can help eliminate up to 50% of excess body weight.
What is tirzepatide?
Tirzepatide belongs to a class of drugs that reduce appetite through neurotransmitters. It is a molecule that acts by simulating the action of two intestinal hormones, GLP-1 and GIP, which are “incretin” hormones that link the absorption of nutrients from the gastrointestinal tract with the secretion of pancreatic hormones. They are released as part of a meal, after the ingestion and absorption of glucose, protein and fat, and provide one of the physiological connections between food and insulin release.
Differences between GLP-1 and GIP
Basically, GLP-1 is a hormone secreted in the gut when we eat. It triggers insulin production in the pancreas when glucose is high, which slows digestion and promotes a feeling of satiety.
GIP, in turn, is a 42 amino acid peptide hormone (bits of protein), a gastric inhibitor, or a glucose-dependent insulinotropic peptide. This hormone targets the beta cells of the pancreas and stimulates them better insulin secretion. Numerous genetic association studies link GIP to the regulation of insulin, glucose, lipids and body weight.
When is the use of tirzepatide indicated?
The decision to initiate drug therapy in people considered to be overweight should be made later consideration of risks and benefits, and the goals must be clear. “The main focus of this treatment for people considered to be overweight is long-term weight reduction and overall health improvement,” says nutritionist Dr. Ronan Araujo.
Tirzepatide is given as a weekly subcutaneous injection. Side effects are manageable and mild in most cases. But, like any other drug, monitoring and medical advice are extremely necessary.
Changes in habits are also needed with the use of the medicine
The doctor. Ronan Araujo points out that it is essential that drugs, like any other type of procedure, are used together eat healthyphysical activity and behavior modification, as the use of drugs without these changes is often ineffective.
“This drug has shown results in excess of bariatric surgery. We, who work with weight loss, can comment that we are in the decade of the end of bariatric surgery, because only with a drug can we provide superior results in performing the operation “, emphasizes the doctor.
Arrival of the drug in Brazil
The drug has been approved by the US Food and Drug Administration (FDA) for the treatment of overweight, obesity and diabetes. “The forecast of arrival in Brazil is for 2023, and can already be imported into the country”, explains Dr. Ronan Araujo, concluding: “Finally, it is worth remembering that any drug, surgery or intervention only makes sense as part of a comprehensive treatment against obesity, which is a chronic disease and requires long-term monitoring and lifestyle changes“.
by Gabriela Dallo
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Source: Terra
Benjamin Smith is a fashion journalist and author at Gossipify, known for his coverage of the latest fashion trends and industry insights. He writes about clothing, shoes, accessories, and runway shows, providing in-depth analysis and unique perspectives. He’s respected for his ability to spot emerging designers and trends, and for providing practical fashion advice to readers.
