Treatment-resistant depression affects 30% of patients, who do not improve even with medications and therapeutic approaches.
Refractory depression, also known as treatment-resistant depression, is a severe form of the disease that does not respond adequately to usual treatment approaches, such as antidepressant medications and psychotherapy. It is estimated to affect about 30% of patients with depression.
For those battling this persistent form of the disease, new hope arises as research advances and promising alternatives are developed. When depression is not controlled with medications or therapies, other strategies may be considered.
“These therapies include alternative modalities of psychotherapy, such as intensive cognitive behavioral therapy or acceptance and commitment therapy; somatic treatments, such as transcranial magnetic stimulation or electroconvulsive therapy; and innovative approaches such as ketamine infusion,” comments the psychiatrist Cíntia Bragawhich reinforces the importance of rigorous and ongoing patient evaluation.
She also stresses that it is important to consider underlying factors that may contribute to treatment resistance, such as other undiagnosed medical conditions, substance use, and complex psychosocial issues. “The approach needs to be holistic and individualized, involving a multidisciplinary team when possible to address all aspects of the patient’s health,” she says.
Cíntia is a supporter of the use of medical cannabis in the treatment of refractory depression. “Preliminary studies suggest that cannabinoids, such as THC and CBD, can have positive effects on the regulation of mood and stress, acting on the endocannabinoid system, which plays a fundamental role in the modulation of emotions,” the doctor reinforces.
It is important to emphasize that the prescription of medical cannabis for refractory depression must be carried out by a doctor with experience in the field, who will be able to individually evaluate each case and determine the appropriate doses and formulations based on the needs of the patient, always paying attention to his needs. well-being.
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Source: Terra

Ben Stock is a lifestyle journalist and author at Gossipify. He writes about topics such as health, wellness, travel, food and home decor. He provides practical advice and inspiration to improve well-being, keeps readers up to date with latest lifestyle news and trends, known for his engaging writing style, in-depth analysis and unique perspectives.