The study underlined a relationship between a few hours of sleep and the emergence of biomarkers associated with Alzheimer’s
A study by the Pasqual Maragall Foundation Research Center, the Barcelonaβeta Brain Research Center (BBRC), in collaboration with researchers from the University of Bristol, revealed that a few hours of sleep and poor rest are associated with greater possibilities of healthy people develop Alzheimer’s. That is, even without any cognitive reduction, the risk increases.
So far the team has used the data of the largest cohort, the longitudinal cohort study on the prevention of Alzheimer’s dementia (Epad LCS). Consequently, the researchers were able to validate the hypothesis that sleep deprivation is associated with cerebrospinal liquid biomarkers (CSF). This, in turn, provides an increase in future possibilities to develop the disease in people who have no symptoms of dementia.
The study
The team analyzed the data from 1,168 adults of over 50 years. Transversal analyzes have revealed that poor sleep quality is significantly associated with the increase in the T-Tau protein in the cerebrospinal liquid. Among the other discoveries, it has been shown that a brief duration of sleep, less than seven hours per night, is related to higher values than P-Tau and T-Tau, fundamental biomarkers to measure the risk of the preclinical phase of Alzheimer’s disease.
“Our results further strengthen the hypothesis that the interruption of sleep can represent a risk factor for Alzheimer’s disease. Therefore, future research is needed to test the effectiveness of preventive practices. They are designed to improve sleep in the pre-skulls of the disease to reduce the pathology of Alzheimer’s disease” pre-entrusted in the BBRC and one of the main authors of the study.
Sleep anomalies are common in Alzheimer’s disease. The quality of sleep can decrease at the beginning of the preclinical phase of the disease, even when there are no other symptoms. Understanding how and when sleep deprivation contributes to the progression of Alzheimer’s disease is important for the conception and implementation of future therapies. This demonstrates the relevance of the study.
“The epidemiological and experimental data available so far have suggested that sleep anomalies contribute to the risk of Alzheimer’s disease. However, previous studies had limits due to the lack of disease biomarkers. This was because they had a non -transversal design or cause of the small dimension of the champion of the participants”, says Stankeviciute.
Importance of sleep
According to the neurologist of the Israelite hospital Albert Einstein, sleep has always been reparative in the human brain. “The less we sleep, the more brain damage can happen,” he says. He underlines that the risk is even greater for young people, since a non -reviewed sleep prevents brain maturation, which usually takes place up to 25 years. The consequences arise only in the advanced phase of life.
Source: Terra
Ben Stock is a lifestyle journalist and author at Gossipify. He writes about topics such as health, wellness, travel, food and home decor. He provides practical advice and inspiration to improve well-being, keeps readers up to date with latest lifestyle news and trends, known for his engaging writing style, in-depth analysis and unique perspectives.
