The World Health Organization (WHO) recommends exercise as the best option for preventing falls
A study conducted by Brazilian researchers suggests that the practice of physical exercises against resistance, such as weight training, can prevent or delay the symptoms of Alzheimers. The survey was conducted by researchers from Unifesp and USP and published Tuesday (6) in the journal Frontiers in Neuroscience.
While many existing studies focus on the potential of aerobic practiceslike running, against the development of Alzheimer’s, the new research has decided to focus on resistance exercises, which involve muscle contractions against an external force.
“Physical exercise against resistance is increasingly confirmed as an effective strategy to prevent the onset of sporadic symptoms of Alzheimer’s [não associada a uma mutação herdada]which is multifactorial and can be related to aging, or delay it in cases of familial form of the disease,” Beatriz Monteiro Longo, professor of neurophysiology at Unifesp and coordinator of the work, told Folha de São Paulo.
Study
The investigation was conducted on genetically modified mice with a mutation associated with beta-amyloid plaques, proteins that assemble in the central nervous system, impairing synapse transmission and damaging neurons. The accumulation in brain It’s typical of Alzheimer’s.
The mice were divided into groups and subjected to an exercise routine, on an inclined ladder with progressive loading, for four weeks.
At the end of the training a blood test was performed and it was found that the levels of corticosterone (a hormone related to stress and the risk of developing Alzheimer’s) had normalized, equaling those of the control group, and the formation of beta-amyloid plaques in the brains of the animals decreased.
The same type of exercise also reduced hyperlocomotion, an anxiety symptom, in mice with the Alzheimer’s-related phenotype.
With the result, the scientists suggest that strength exercise may help reverse changes in the brain and be an effective way to prevent or delay the symptoms of Alzheimer’s, especially in the non-hereditary form of the disease. They attribute the changes to the anti-inflammatory potential of the practice.
Source: Terra
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