The Herpes-Zoster vaccine can reduce the risk of heart attack and stroke, states the study

The Herpes-Zoster vaccine can reduce the risk of heart attack and stroke, states the study


A new systematic revision and global meta-analysis shows a drop of 18% of cardiovascular events


Summary

Vaccination against herpes-zoster can reduce the risk of heart attack and stroke up to 18%, according to a global study presented at the European Society of Cardiology, although further research is needed to confirm causality.




Vaccination against herpes-zoster, popularly known as a culture, is associated with a significant reduction in the risk of heart attack and stroke (stroke). This is what a new global study said at the Congress of the European Society of Cardiology (ESC 2025), which is happening this week in Madrid, Spain.

Herpes-zoster is caused by the reactivation of the chickenpox-zoster virus (VVZ), the same that causes chickenpox. After the primary infection, it remains latent in the nervous and reactive system, causing herpes zoster.

VVZ can also invade large and small blood vessels in the head, which can lead to inflammation and vascular remodeling. This is believed that this leads to complications such as stroke after the reactivation of the virus.

The study, which is the first global systematic revision of the meta-analysis to fully evaluate evidence on the association between vaccination against disease and cardiovascular events, found a reduction of 18% and 16% of adults aged 18 to 50.

To reach the conclusion, three databases were analyzed by 19 scientific and observational studies, as well as phase 3 randomized clinical studies that evaluated the effect of immunizers on cardiovascular events, following the guidelines of Cochrane. In nine of them, 53.3% of the participants were male and, in seven of them, had a medical age from 53 to 74 years.

“Although our results are encouraging, there are some limitations on the available data that we study. Almost all the tests are derived from observational studies, which are subject to prejudices and should not be used to deduce causality. All studies used in the meta-analysis have the main objective to study the use of cardiovascula the need for further research in this sector”, explains Charles Williams, medical director of the vaccines of the vaccines GSK’s global and author of the study.

In previous research, a transitory increase in the risk of stroke and heart attack after Herpes Zoster, but there is still no confirmation if the vaccination against the disease can actually reduce the cardiovascular risk, says ESC.

Source: Terra

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