In the era of obesity and overweight, many doubts arise about the use of Ozempic and Mounjaro, current favorites of celebrities! These are alarming numbers: 56% of Brazilian adults suffer from obesity or overweight. And this disease, which is chronic, is already considered a global epidemic according to the World Health Organization (WHO). THE […]
In the era of obesity and overweight, many doubts arise about the use of Ozempic and Mounjaro, current favorites of celebrities!
These are alarming numbers: 56% of Brazilian adults suffer from obesity or overweight. And this disease, which is chronic, is already considered a global epidemic according to the World Health Organization (WHO). The treatment is long and requires determination and specialized medical monitoring.
But in the fight against extra pounds, drugs such as Ozempic and Mounjaro are in the spotlight. Raphaela Paes, an endocrinologist working at Segmedic, explains that these drugs are indicated for the treatment of type 2 diabetes, as they both help improve glycemic control. “Additionally, medications have been prescribed off-label to treat obesity or overweight associated with other health conditions. In addition to lifestyle changes, they are not sufficient to promote significant weight loss,” he explains.
The differences between the drugs
According to the doctor, the main difference between Ozempic (Semaglutide) and Mounjaro (Tirzepatide) is in the mechanism of action. Explaining it more technically, Ozempic is a GLP-1 receptor agonist, meaning it works by increasing satiety, reducing appetite, delaying gastric emptying, and controlling blood glucose levels. “Mounjaro is a dual agonist, acting on both GLP-1 and GIP receptors. This combination of mechanisms makes Mounjaro even more effective in weight loss and glycemic control than Ozempic,” he comments.
These treatments are not suitable for everyone!
Raphaela points out that both drugs have important contraindications. “They should not be used by people with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. They are also contraindicated in case of allergy to the components of the formula, during pregnancy or breastfeeding and in patients with severe renal or hepatic impairment, although the final decision in these cases depends on medical evaluation. Patients with a history of pancreatitis should also be carefully evaluated before starting treatment,” he says.
Against obesity, a new lifestyle
It is essential to adopt sustainable lifestyle changes for the success of treatment. “Nutrition education must be given priority, with a balanced diet suited to the patient’s needs. Regular physical activity, including weight training and aerobic exercise, is essential to help maintain weight and preserve health. muscle mass. Furthermore, monitoring with a multidisciplinary team, composed of a doctor, nutritionist, psychologist, physical educator, is necessary to guide and offer continuous support”, he advises.
Finally, long-term planning is key, as the body tends to regain lost weight after stopping treatment. “In some cases, doctors may choose to maintain the use of medications at lower doses or intermittently, depending on each patient’s assessment. This, combined with lifestyle changes, helps ensure long-lasting and effective results. avoid the feared ‘accordion effect'”, concludes Raffaella.
Source: Terra
Ben Stock is a lifestyle journalist and author at Gossipify. He writes about topics such as health, wellness, travel, food and home decor. He provides practical advice and inspiration to improve well-being, keeps readers up to date with latest lifestyle news and trends, known for his engaging writing style, in-depth analysis and unique perspectives.
