What do Japanese women drink to stay young?

What is glutathione and why is it important for the body

Glutathione is an antioxidant, that is, a substance that slows down the aging of cells and the body as a whole. It is made up of three amino acids: glutamine, cysteine ​​and glycine^one.

One of the causes of aging is free radicals. These are substances that are constantly produced in the body as by-products during metabolism and other physiological processes.². In small amounts, free radicals are essential for memory, coordination, and other brain functions. But when these substances accumulate, they oxidize the cells of all tissues and organs. For example, they destroy the protective barrier of the skin, due to which it becomes dry, age spots and wrinkles form.³. Free radicals damage the follicles – hair turns gray and often falls out^four. Oxidation of cells affects not only appearance: muscles can weaken, vision deteriorates, and immunity decreases.².

Glutathione helps fight cell oxidation. It is produced in the liver⁵with blood spreads throughout the body and blocks the action of free radicals, after which it removes them^one.

What happens when there is a lack of glutathione

Glutathione is produced naturally in the body, but its synthesis decreases with age. Many women notice signs of aging in their 40s and 45s when antioxidant levels drop by 20% compared to their 20s and 30s.⁶. Synthesis of glutathione is also reduced by frequent stress and solar ultraviolet, so some deep wrinkles may appear before the age of 40.^7.8.

Nothing prevents free radicals from oxidizing cells, so the skin becomes dull and loses elasticity, hair falls out, nails become brittle. May weaken immunity and often experience fatigue².

It turns out a vicious circle: the body ages → glutathione is produced in smaller quantities → this further exacerbates age-related signs.

How to replenish and maintain the level of glutathione in the body

Glutathione is found in asparagus, carrots, oranges, apples⁹. It is also added to some dietary supplements. But if you take an antioxidant in this form, it will not benefit the body. The fact is that under the influence of hydrochloric acid in the stomach, glutathione breaks down into amino acids.^tenand they alone do not block free radicals. Therefore, before the antioxidant had to be injected directly into the blood – through a dropper or as an injection.

But now there is a way to take glutathione, without injections and drips. An acetyl group was added to its molecule, a compound that prevents the substance from breaking down in the stomach. The antioxidant is absorbed into the cells in its original form and does not lose its properties.^eleven. The result was glutathione, which is absorbed in the form of tablets in the same way as in the form of injections and droppers.

In Russia, the antioxidant in the form of tablets is produced by Evalar. Additive “Acetyl Glutathione” helps increase glutathione levels in the body and slow down aging¹².

That’s how “Acetyl Glutathione” from Evalar helps to slow down aging:

• fights free radicals, protecting body cells from oxidative damage;
• can prevent the development of inflammatory reactions;
• promotes the restoration of damaged tissues;
• helps to strengthen the immune system and less likely to get sick
• promotes detoxification of the body (removal of toxic substances and heavy metals)¹².

You can buy Acetyl-Glutathione Evalar on the website evalar.ru,
fitomarket.com,
apteka.ru,
wildberries

and
ozon.ru.

dietary supplement. is not a drug.

Sources:

• National Library of Medicine: Henry Jay Forman. — Glutathione: an overview of its protective roles, measurement, and biosynthesis. – 2008. – Electronic resource – URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696075/
• Pharmacognosy Reviews: V Lobo, A Patil. – Free Radicals, Antioxidants and Functional Foods: Impact on Human Health. – 2010. – Electronic resource – URL: http://www.phcogrev.com/article/2010/4/8/1041030973-784770902
• Dermatology Research and Practice: Borut Poljsak, Raja Dahmane. – Free Radicals and Extrinsic Skin Aging. – 2011. – Electronic resource – URL: https://www.hindawi.com/journals/drp/2012/135206/
• International Journal of Trichology: Ralph M Trueb. – Oxidative Stress in Aging of Hair. – 2009. – Electronic resource – URL: https://www.ijtrichology.com/article.asp?issn=0974-7753;year=2009;volume=1;issue=1;spage=6;epage=14;aulast=Trueb
• National Library of Medicine: Shelly C. Lu. — Glutathione synthesis. – 2013. – Electronic resource – URL: https://pubmed.ncbi.nlm.nih.gov/22995213/
• Chin Med: Wang Qui-lin, Wang Shu-ren, Ding Yi. — Age-related changes of the redox state of glutathione in plasma. – 2005. – Electronic resource – URL: https://medcentral.net/doi/pdf/10.5555/cmj.0366-6999.118.18.p1560.01
• Neuroscience & Biobehavioral Reviews: Ioannis Zalachoras, Fiona Hollis. — Therapeutic potential of glutathione-enhancers in stress-related psychopathologies. — 2020. — Electronic resource — URL: https://www.sciencedirect.com/science/article/abs/pii/S0149763419311133
• Biochem Soc Symp.: R.M. Tyrrell. – Ultraviolet radiation and free radical damage to skin. – 1995. – Electronic resource – URL: https://pubmed.ncbi.nlm.nih.gov/8660402/
• National Library of Medicine: Deanna M. Minich, Benjamin I Brown. — A Review of Dietary (Phyto) Nutrients for Glutathione Support. — 2019. — Electronic resource — URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770193/
• International Journal of Clinical Nutrition & Dietetics: Sergio Fanelli, A. Francioso. – Oral Administration of S-acetyl-glutathione: Impact on the Levels of Glutathione in Plasma and in Erythrocytes of Healthy Volunteers. — 2018 — Electronic resource — URL: https://www.semanticscholar.org/paper/Oral-Administration-of-S-acetyl-glutathione%3A-Impact-Fanelli-Francioso/fb2b6ad5ffd26d47b18fdf9324779b69da49dbcc

• National Library of Medicine: ME Anderson, F Powrie, RN Puri, A Meister. — Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione. – 1985. – Electronic resource – URL: https://pubmed.ncbi.nlm.nih.gov/4004275/
• Instructions for the drug “Acetyl-glutathione” from Evalar. — Electronic resource — URL: https://shop.evalar.ru/catalog/anti-age/acetyl-glutathione/#instruction

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